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莫西芬

网络tamoxifen

莫西芬

莫西芬

莫西芬

tamoxifen

莫西芬 (tamoxifen) 应用领域的先驱同时也是荣获英帝国勋章的军官 V. Craig Jordan

2

Tamoxifen , a drug that blocks the effects of estrogen on the body, is often used to treat women whose tumors are sensitive to estrogen .

他莫西芬是体内雌激素效应的抑制剂，常被用于治疗女性患者体内对雌激素敏感的肿瘤的治疗。

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Gynecomastia can be painful and feel tender. This can be treated with medications like the antiestrogen drug tamoxifen .

男性乳房发育症是痛苦的并有触痛感，它的治疗可以采用诸如抗雌激素药他莫西芬等药物。

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Now it appears that some women will do at least as well if they're treated with tamoxifen .

现在看起来一些妇女用它莫西芬治疗的效果会很好。

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Tamoxifen is usually given to women with oestrogen-sensitive breast cancer .

它莫西芬通常用于治疗雌激素敏感的乳癌女性。

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For women with the gene variant linked to poor response to tamoxifen treatment , other treatment strategies would be a better choice.

携带该基因变异体的妇女，对它莫西芬治疗耐受，是以其他的治疗方案会更好。

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Tamoxifen , which cancels out the sex hormone oestrogen, was first used to fight breast cancer more than 40 years ago.

他莫西芬，被用来治疗女性不孕症以及乳腺癌有 40多年了。

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Such women carry a version of a gene called CYP2D6 that makes tamoxifen work better.

这些妇女携带有 CYP2D6 基因的一个变异体，该变异体使它莫西芬的作用效果更好。

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'This is simply a situation in which [Seroxat] impairs the effectiveness of tamoxifen , ' they said .

“这里的情况很简单，【塞尔特】削弱了它莫西芬的效用。”研究者说。

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In the 46% of women with the "good " gene , tamoxifen works as well as newer drugs .

在 46%携带该 “好 ”基因的妇女中，它莫西芬与新药的治疗下场不异。

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In fact , for women who were followed for 5 years or more , adherence with tamoxifen therapy was modest (49%).

实际上，依从他莫西芬疗法并持续服用了 5 年或更长时间的患者比例是适中的（49%）。

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